Research

Understanding the biology, and how it shows in blood

We study the biological processes that drive Alzheimer's disease and other dementias, and develop assays that measure how that biology is reflected in blood. Each project brings us closer to diagnosis, monitoring and care based on biology.

New assay formats

Next-generation blood tests that capture more of the biology behind neurodegeneration.

Unlocking tau heterogeneity through post-translational modification biomarkers in plasma Read project →

Abstract flowing glass-like structure in blue

Tracking the emergence of tau aggregation Read project →

A hand pointing at brain scans on a light board

Tracing the origins of tau in blood Read project →

A scientist in safety glasses working at a microscope

Biomarkers for mixed neurodegenerative pathologies Read project →

Increase of access

Taking biomarker testing beyond the clinic, to the people who need it most.

An older woman at home, looking out of a sunlit window

Bringing Alzheimer's blood testing to people, wherever they are Read project →

Clinical implementation

Turning biomarker results into decisions clinicians can act on.

A row of identical laboratory tubes filled with blue liquid

One scale for every p-tau217 blood test Read project →

Two clinicians reviewing data together on a computer screen

Turning biomarker data into clinical insight Read project →

Funded research

Active funded projects

Alongside the programmes above, the lab leads and contributes blood biomarker work to studies funded by the NIH, the U.S. Department of Defense and private foundations, with collaborators across the country.